Biomarkers of Coronary Artery Disease: The Promise of the Transcriptome

The last years have witnessed tremendous technical advances in the field of transcriptomics that enable the simultaneous assessment of nearly all transcripts expressed in a tissue at a given time. These advances harbor the potential to gain a better understanding of the complex biological systems an...

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Detalles Bibliográficos
Autores principales: Siemelink, Marten Antoon, Zeller, Tanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Cardiovascular Genomics (R McPherson, Section Editor)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231210/
https://www.ncbi.nlm.nih.gov/pubmed/24950674
http://dx.doi.org/10.1007/s11886-014-0513-4
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author Siemelink, Marten Antoon
Zeller, Tanja
author_facet Siemelink, Marten Antoon
Zeller, Tanja
author_sort Siemelink, Marten Antoon
collection PubMed
description The last years have witnessed tremendous technical advances in the field of transcriptomics that enable the simultaneous assessment of nearly all transcripts expressed in a tissue at a given time. These advances harbor the potential to gain a better understanding of the complex biological systems and for the identification and development of novel biomarkers. This article will review the current knowledge of transcriptomics biomarkers in the cardiovascular field and will provide an overview about the promises and challenges of the transcriptomics approach for biomarker identification.
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spelling pubmed-42312102014-11-18 Biomarkers of Coronary Artery Disease: The Promise of the Transcriptome Siemelink, Marten Antoon Zeller, Tanja Curr Cardiol Rep Cardiovascular Genomics (R McPherson, Section Editor) The last years have witnessed tremendous technical advances in the field of transcriptomics that enable the simultaneous assessment of nearly all transcripts expressed in a tissue at a given time. These advances harbor the potential to gain a better understanding of the complex biological systems and for the identification and development of novel biomarkers. This article will review the current knowledge of transcriptomics biomarkers in the cardiovascular field and will provide an overview about the promises and challenges of the transcriptomics approach for biomarker identification. Springer US 2014-06-21 2014 /pmc/articles/PMC4231210/ /pubmed/24950674 http://dx.doi.org/10.1007/s11886-014-0513-4 Text en © Springer Science+Business Media New York 2014
spellingShingle Cardiovascular Genomics (R McPherson, Section Editor)
Siemelink, Marten Antoon
Zeller, Tanja
Biomarkers of Coronary Artery Disease: The Promise of the Transcriptome
title Biomarkers of Coronary Artery Disease: The Promise of the Transcriptome
title_full Biomarkers of Coronary Artery Disease: The Promise of the Transcriptome
title_fullStr Biomarkers of Coronary Artery Disease: The Promise of the Transcriptome
title_full_unstemmed Biomarkers of Coronary Artery Disease: The Promise of the Transcriptome
title_short Biomarkers of Coronary Artery Disease: The Promise of the Transcriptome
title_sort biomarkers of coronary artery disease: the promise of the transcriptome
topic Cardiovascular Genomics (R McPherson, Section Editor)
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231210/
https://www.ncbi.nlm.nih.gov/pubmed/24950674
http://dx.doi.org/10.1007/s11886-014-0513-4
work_keys_str_mv AT siemelinkmartenantoon biomarkersofcoronaryarterydiseasethepromiseofthetranscriptome
AT zellertanja biomarkersofcoronaryarterydiseasethepromiseofthetranscriptome

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