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Splicing mutation analysis reveals previously unrecognized pathways in lymph node-invasive breast cancer

Somatic mutations reported in large-scale breast cancer (BC) sequencing studies primarily consist of protein coding mutations. mRNA splicing mutation analyses have been limited in scope, despite their prevalence in Mendelian genetic disorders. We predicted splicing mutations in 442 BC tumour and mat...

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Detalles Bibliográficos
Autores principales: Dorman, Stephanie N., Viner, Coby, Rogan, Peter K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231324/
https://www.ncbi.nlm.nih.gov/pubmed/25394353
http://dx.doi.org/10.1038/srep07063