Cargando…

Exendin-4 and sitagliptin protect kidney from ischemia-reperfusion injury through suppressing oxidative stress and inflammatory reaction

BACKGROUND: This study tested the hypothesis that exendin-4 and sitagliptin can effectively protect kidney from acute ischemia-reperfusion (IR) injury. METHODS: Adult SD-rats (n = 48) equally divided into group 1 (sham control), group 2 (IR injury), group 3 [IR + sitagliptin 600 mg/kg at post-IR 1,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Yen-Ta, Tsai, Tzu-Hsien, Yang, Chih-Chau, Sun, Cheuk-Kwan, Chang, Li-Teh, Chen, Hung-Hwa, Chang, Chia-Lo, Sung, Pei-Hsun, Zhen, Yen-Yi, Leu, Steve, Chang, Hsueh-Wen, Chen, Yung-Lung, Yip, Hon-Kan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231365/ https://www.ncbi.nlm.nih.gov/pubmed/24161164 http://dx.doi.org/10.1186/1479-5876-11-270

Ejemplares similares

Adipose-Derived Mesenchymal Stem Cell Protects Kidneys against Ischemia-Reperfusion Injury through Suppressing Oxidative Stress and Inflammatory Reaction
por: Chen, Yen-Ta, et al.
Publicado: (2011)

Inhibition of dipeptidyl peptidase-IV enzyme activity protects against myocardial ischemia-reperfusion injury in rats
por: Chua, Sarah, et al.
Publicado: (2014)

Cyclosporine-assisted adipose-derived mesenchymal stem cell therapy to mitigate acute kidney ischemia–reperfusion injury
por: Chen, Yen-Ta, et al.
Publicado: (2013)

Autologous Transplantation of Adipose-Derived Mesenchymal Stem Cells Markedly Reduced Acute Ischemia-Reperfusion Lung Injury in a Rodent Model
por: Sun, Cheuk-Kwan, et al.
Publicado: (2011)

Intra-coronary administration of tacrolimus markedly attenuates infarct size and preserves heart function in porcine myocardial infarction
por: Chua, Sarah, et al.
Publicado: (2012)

Combination of cilostazol and clopidogrel attenuates Rat critical limb ischemia
por: Sheu, Jiunn-Jye, et al.
Publicado: (2012)

Levels and values of circulating endothelial progenitor cells, soluble angiogenic factors, and mononuclear cell apoptosis in liver cirrhosis patients
por: Chen, Chih-Hung, et al.
Publicado: (2012)

Continuing Exposure to Low-Dose Nonylphenol Aggravates Adenine-Induced Chronic Renal Dysfunction and Role of Rosuvastatin Therapy
por: Yen, Chia-Hung, et al.
Publicado: (2012)

Reducing TRPC1 Expression through Liposome-Mediated siRNA Delivery Markedly Attenuates Hypoxia-Induced Pulmonary Arterial Hypertension in a Murine Model
por: Sun, Cheuk-Kwan, et al.
Publicado: (2014)

Paradoxical impairment of angiogenesis, endothelial function and circulating number of endothelial progenitor cells in DPP4-deficient rat after critical limb ischemia
por: Sun, Cheuk-Kwan, et al.
Publicado: (2013)

Combination of cyclosporine and erythropoietin improves brain infarct size and neurological function in rats after ischemic stroke
por: Yuen, Chun-Man, et al.
Publicado: (2011)

Obesity suppresses circulating level and function of endothelial progenitor cells and heart function
por: Tsai, Tzu-Hsien, et al.
Publicado: (2012)

Administered circulating microparticles derived from lung cancer patients markedly improved angiogenesis, blood flow and ischemic recovery in rat critical limb ischemia
por: Sheu, Jiunn-Jye, et al.
Publicado: (2015)

Apoptotic adipose-derived mesenchymal stem cell therapy protects against lung and kidney injury in sepsis syndrome caused by cecal ligation puncture in rats
por: Sung, Pei-Hsun, et al.
Publicado: (2013)

DPP-4 enzyme deficiency protects kidney from acute ischemia-reperfusion injury: role for remote intermittent bowel ischemia-reperfusion preconditioning
por: Chen, Yen-Ta, et al.
Publicado: (2017)

Innate immune response after acute myocardial infarction and pharmacomodulatory action of tacrolimus in reducing infarct size and preserving myocardial integrity
por: Sheu, Jiunn-Jye, et al.
Publicado: (2013)

Combination therapy of exendin-4 and allogenic adipose-derived mesenchymal stem cell preserved renal function in a chronic kidney disease and sepsis syndrome setting in rats
por: Chen, Chih-Hung, et al.
Publicado: (2017)

Impact of obesity control on circulating level of endothelial progenitor cells and angiogenesis in response to ischemic stimulation
por: Chen, Yung-Lung, et al.
Publicado: (2012)

Impact of apoptotic adipose-derived mesenchymal stem cells on attenuating organ damage and reducing mortality in Rat sepsis syndrome induced by cecal puncture and ligation
por: Chang, Chia-Lo, et al.
Publicado: (2012)

Early combined treatment with sildenafil and adipose-derived mesenchymal stem cells preserves heart function in rat dilated cardiomyopathy
por: Lin, Yu-Chun, et al.
Publicado: (2010)

Effect of obesity reduction on preservation of heart function and attenuation of left ventricular remodeling, oxidative stress and inflammation in obese mice
por: Wang, Hui-Ting, et al.
Publicado: (2012)

Levels and values of lipoprotein-associated phospholipase A(2), galectin-3, RhoA/ROCK, and endothelial progenitor cells in critical limb ischemia: pharmaco-therapeutic role of cilostazol and clopidogrel combination therapy
por: Sheu, Jiunn-Jye, et al.
Publicado: (2014)

Myocardium-derived conditioned medium improves left ventricular function in rodent acute myocardial infarction
por: Leu, Steve, et al.
Publicado: (2011)

Adipose-derived mesenchymal stem cells markedly attenuate brain infarct size and improve neurological function in rats
por: Leu, Steve, et al.
Publicado: (2010)

Levels of Circulating Microparticles in Lung Cancer Patients and Possible Prognostic Value
por: Tseng, Chia-Cheng, et al.
Publicado: (2013)

Xenogeneic human umbilical cord-derived mesenchymal stem cells reduce mortality in rats with acute respiratory distress syndrome complicated by sepsis
por: Lee, Fan-Yen, et al.
Publicado: (2017)

Extracorporeal shockwave against inflammation mediated by GPR120 receptor in cyclophosphamide-induced rat cystitis model
por: Chen, Yi-Ling, et al.
Publicado: (2018)

AG490 suppresses EPO-mediated activation of JAK2-STAT but enhances blood flow recovery in rats with critical limb ischemia
por: Chai, Han-Tan, et al.
Publicado: (2016)

Combined melatonin-adipose derived mesenchymal stem cells therapy effectively protected the testis from testicular torsion-induced ischemia-reperfusion injury
por: Chen, Yen-Ta, et al.
Publicado: (2021)

Effect of erythropoietin therapy on clinical outcome in patients after acute ischemic stroke: a debatable issue
por: Yuen, Chun-Man, et al.
Publicado: (2011)

tPA-MMP-9 Axis Plays a Pivotal Role in Mobilization of Endothelial Progenitor Cells from Bone Marrow to Circulation and Ischemic Region for Angiogenesis
por: Leu, Steve, et al.
Publicado: (2016)

Exendin-4, a glucagon-like peptide-1 analogue accelerates healing of chronic gastric ulcer in diabetic rats
por: Chen, Yen-Cheng, et al.
Publicado: (2017)

Xenogeneic and Allogeneic Mesenchymal Stem Cells Effectively Protect the Lung Against Ischemia-reperfusion Injury Through Downregulating the Inflammatory, Oxidative Stress, and Autophagic Signaling Pathways in Rat
por: Lin, Kun-Chen, et al.
Publicado: (2020)

Long-Lasting Exendin-4-Loaded PLGA Nanoparticles Ameliorate Cerebral Ischemia/Reperfusion Damage in Diabetic Rats
por: Chung, Cheng-Hsun, et al.
Publicado: (2022)

Higher neutrophil counts and neutrophil-to-lymphocyte ratio predict prognostic outcomes in patients after non-atrial fibrillation-caused ischemic stroke
por: Fang, Yen-Nan, et al.
Publicado: (2017)

Effect of erythropoietin on level of circulating endothelial progenitor cells and outcome in patients after acute ischemic stroke
por: Yip, Hon-Kan, et al.
Publicado: (2011)

Investigated the safety of intra-renal arterial transfusion of autologous CD34+ cells and time courses of creatinine levels, endothelial dysfunction biomarkers and micro-RNAs in chronic kidney disease patients-phase I clinical trial
por: Lee, Mel S., et al.
Publicado: (2017)

Exendin-4 improves resistance to Listeria monocytogenes infection in diabetic db/db mice
por: Liu, Hsien Yueh, et al.
Publicado: (2012)

Circulating Endothelial-Derived Activated Microparticle: A Useful Biomarker for Predicting One-Year Mortality in Patients with Advanced Non-Small Cell Lung Cancer
por: Wang, Chin-Chou, et al.
Publicado: (2014)

Exendin-4 ameliorates cardiac ischemia/reperfusion injury via caveolae and caveolins-3
por: Tsutsumi, Yasuo M, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_08780j1hfi215vvd3j29otk5ma