Efficacy of an oral and tropically stable lipid-based formulation of Amphotericin B (iCo-010) in an experimental mouse model of systemic candidiasis

OBJECTIVE: An oral lipid based formulation that exhibits tropical stability (iCo-010) was developed to enhance the absorption of orally administered amphotericin B (AmB). iCo-010 has previously shown high efficacy in an acute model of systemic candidiasis in rats, directing the focus of this study t...

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Detalles Bibliográficos
Autores principales: Ibrahim, Fady, Sivak, Olena, Wasan, Ellen K, Bartlett, Karen, Wasan, Kishor M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231414/
https://www.ncbi.nlm.nih.gov/pubmed/24164705
http://dx.doi.org/10.1186/1476-511X-12-158

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231414/
https://www.ncbi.nlm.nih.gov/pubmed/24164705
http://dx.doi.org/10.1186/1476-511X-12-158

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