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HIV-1 Tat protein binds to TLR4-MD2 and signals to induce TNF-α and IL-10

BACKGROUND: HIV-1 infection results in hyper-immune activation and immunological disorders as early as the asymptomatic stage. Here, we hypothesized that during early HIV-1 infection, HIV-1 Tat protein acts on monocytes/macrophages to induce anti-inflammatory and proinflammatory cytokines and partic...

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Detalles Bibliográficos
Autores principales:	Ben Haij, Nawal, Leghmari, Kaoutar, Planès, Rémi, Thieblemont, Nathalie, Bahraoui, Elmostafa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231456/ https://www.ncbi.nlm.nih.gov/pubmed/24165011 http://dx.doi.org/10.1186/1742-4690-10-123

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