Vectorial secretion of interleukin-8 mediates autocrine signalling in intestinal epithelial cells via apically located CXCR1

BACKGROUND: In the intestinal mucosa, several adaptations of TLR signalling have evolved to avoid chronic inflammatory responses to the presence of commensal microbes. Here we investigated whether polarized monolayers of intestinal epithelial cells might regulate inflammatory responses by secreting...

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Detalles Bibliográficos
Autores principales: Rossi, Oriana, Karczewski, Jurgen, Stolte, Ellen H, Brummer, Robert J M, van Nieuwenhoven, Michiel A, Meijerink, Marjolein, van Neerven, Joost R J, van Ijzendoorn, Sven C D, van Baarlen, Peter, Wells, Jerry M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231470/
https://www.ncbi.nlm.nih.gov/pubmed/24164922
http://dx.doi.org/10.1186/1756-0500-6-431

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