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One patient - three head and neck primaries: nasopharyngeal, tongue and thyroid cancers
BACKGROUND: We report a rare case of three head and neck malignancies in one patient. Squamous cell carcinoma of tongue and papillary thyroid carcinoma occurred as metachronous cancers in a patient with primary nasopharyngeal carcinoma. These three pathologically distinct malignancies of head and ne...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231545/ https://www.ncbi.nlm.nih.gov/pubmed/24164964 http://dx.doi.org/10.1186/1756-0500-6-432 |
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author | Fareed, Muhammad Mohsin Al Amro, Abdullah Bayoumi, Yasser AlQahtani, Khalid HA Fatani, Hanadi A Tunio, Mutahar Ali Khalid, Farhan |
author_facet | Fareed, Muhammad Mohsin Al Amro, Abdullah Bayoumi, Yasser AlQahtani, Khalid HA Fatani, Hanadi A Tunio, Mutahar Ali Khalid, Farhan |
author_sort | Fareed, Muhammad Mohsin |
collection | PubMed |
description | BACKGROUND: We report a rare case of three head and neck malignancies in one patient. Squamous cell carcinoma of tongue and papillary thyroid carcinoma occurred as metachronous cancers in a patient with primary nasopharyngeal carcinoma. These three pathologically distinct malignancies of head and neck region in one patient is a rare phenomenon and is not reported so far. CASE PRESENTATION: A 60 year old Saudi female patient presented in March 2011 with locally advanced nasopharyngeal carcinoma. After completion of concurrent chemoradiation in June 2011, she developed two new primaries i-e thyroid cancer and tongue cancer in May 2012 along with recurrent nasopharyngeal carcinoma. We discuss histopathologic features, diagnostic tools and treatment modalities for this rarely existing case. CONCLUSION: High index of suspicion and thorough work up is essential in follow up of patients with head and neck primary cancers. The effect of field cancerization and environmental factors need to be explored in greater depths in such selected cases. However, which patients are at increased risk of triplet primaries, is still unknown. |
format | Online Article Text |
id | pubmed-4231545 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-42315452014-11-15 One patient - three head and neck primaries: nasopharyngeal, tongue and thyroid cancers Fareed, Muhammad Mohsin Al Amro, Abdullah Bayoumi, Yasser AlQahtani, Khalid HA Fatani, Hanadi A Tunio, Mutahar Ali Khalid, Farhan BMC Res Notes Case Report BACKGROUND: We report a rare case of three head and neck malignancies in one patient. Squamous cell carcinoma of tongue and papillary thyroid carcinoma occurred as metachronous cancers in a patient with primary nasopharyngeal carcinoma. These three pathologically distinct malignancies of head and neck region in one patient is a rare phenomenon and is not reported so far. CASE PRESENTATION: A 60 year old Saudi female patient presented in March 2011 with locally advanced nasopharyngeal carcinoma. After completion of concurrent chemoradiation in June 2011, she developed two new primaries i-e thyroid cancer and tongue cancer in May 2012 along with recurrent nasopharyngeal carcinoma. We discuss histopathologic features, diagnostic tools and treatment modalities for this rarely existing case. CONCLUSION: High index of suspicion and thorough work up is essential in follow up of patients with head and neck primary cancers. The effect of field cancerization and environmental factors need to be explored in greater depths in such selected cases. However, which patients are at increased risk of triplet primaries, is still unknown. BioMed Central 2013-10-28 /pmc/articles/PMC4231545/ /pubmed/24164964 http://dx.doi.org/10.1186/1756-0500-6-432 Text en Copyright © 2013 Fareed et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Fareed, Muhammad Mohsin Al Amro, Abdullah Bayoumi, Yasser AlQahtani, Khalid HA Fatani, Hanadi A Tunio, Mutahar Ali Khalid, Farhan One patient - three head and neck primaries: nasopharyngeal, tongue and thyroid cancers |
title | One patient - three head and neck primaries: nasopharyngeal, tongue and thyroid cancers |
title_full | One patient - three head and neck primaries: nasopharyngeal, tongue and thyroid cancers |
title_fullStr | One patient - three head and neck primaries: nasopharyngeal, tongue and thyroid cancers |
title_full_unstemmed | One patient - three head and neck primaries: nasopharyngeal, tongue and thyroid cancers |
title_short | One patient - three head and neck primaries: nasopharyngeal, tongue and thyroid cancers |
title_sort | one patient - three head and neck primaries: nasopharyngeal, tongue and thyroid cancers |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231545/ https://www.ncbi.nlm.nih.gov/pubmed/24164964 http://dx.doi.org/10.1186/1756-0500-6-432 |
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