Oral carvedilol in escalating doses in the acute treatment of atrial fibrillation

OBJECTIVE: To study the efficacy of oral carvedilol in acute treatment of atrial fibrillation (AF) with fast ventricular rate. MATERIALS AND METHODS: In an open-label, single-arm trial, oral carvedilol was administered to 35 patients of AF in escalating doses from 3.125 mg o.d. to 12.5 mg b.i.d. RES...

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Detalles Bibliográficos
Autores principales: Chitrapu, Ravi Venkatachelam, Rao, Pentakota Ramana, Reddy, Gangireddy Venkateswara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231552/
https://www.ncbi.nlm.nih.gov/pubmed/25422563
http://dx.doi.org/10.4103/0976-500X.142430
Descripción
Sumario:OBJECTIVE: To study the efficacy of oral carvedilol in acute treatment of atrial fibrillation (AF) with fast ventricular rate. MATERIALS AND METHODS: In an open-label, single-arm trial, oral carvedilol was administered to 35 patients of AF in escalating doses from 3.125 mg o.d. to 12.5 mg b.i.d. RESULTS: A successful result was seen in 25 patients (71.4%) with 4 converting to sinus rhythm, rate control to less than 90 bpm in 16 and a 20% rate reduction in 5 patients. Two patients developed hypotension needing withdrawal of the drug. CONCLUSION: Escalating doses of oral carvedilol can be effectively and safely used in the acute treatment of AF with fast ventricular rate.

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