Ganciclovir–tenofovir interaction leading to tenofovir-induced nephrotoxicity

Viral enteritis is an important gastrointestinal disorder in human immunodeficiency virus (HIV)-infected patients. Cytomegalovirus (CMV) is the most common opportunistic agent in these patients. As ganciclovir and tenofovir are the most commonly used drugs for the treatment of CMV and HIV infection,...

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Detalles Bibliográficos
Autores principales: Soanker, Radhika, Udutha, Shobha Jagdish Chandra, Subbalaxmi, Malladi V S, Raju, YSN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231561/
https://www.ncbi.nlm.nih.gov/pubmed/25422572
http://dx.doi.org/10.4103/0976-500X.142452
Descripción
Sumario:Viral enteritis is an important gastrointestinal disorder in human immunodeficiency virus (HIV)-infected patients. Cytomegalovirus (CMV) is the most common opportunistic agent in these patients. As ganciclovir and tenofovir are the most commonly used drugs for the treatment of CMV and HIV infection, respectively, this case report showcases the potentiality of drug interaction as well as the safety measures to be taken when using these two drugs together in unavoidable situations.

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