NIAM-Deficient Mice Are Predisposed to the Development of Proliferative Lesions including B-Cell Lymphomas

Nuclear Interactor of ARF and Mdm2 (NIAM, gene designation Tbrg1) is a largely unstudied inhibitor of cell proliferation that helps maintain chromosomal stability. It is a novel activator of the ARF-Mdm2-Tip60-p53 tumor suppressor pathway as well as other undefined pathways important for genome main...

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Detalles Bibliográficos
Autores principales: Reed, Sara M., Hagen, Jussara, Muniz, Viviane P., Rosean, Timothy R., Borcherding, Nick, Sciegienka, Sebastian, Goeken, J. Adam, Naumann, Paul W., Zhang, Weizhou, Tompkins, Van S., Janz, Siegfried, Meyerholz, David K., Quelle, Dawn E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231569/
https://www.ncbi.nlm.nih.gov/pubmed/25393878
http://dx.doi.org/10.1371/journal.pone.0112126

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