IGF-I increases markers of osteoblastic activity and reduces bone resorption via osteoprotegerin and RANK-ligand

BACKGROUND: Bone is one of the major target tissues for Insulin-like Growth Factor I (IGF-I). Low doses of IGF-I were able to improve liver-associated osteopenia. In the present work, a model of partial IGF-I deficiency was used in order to provide insight into the mechanisms of the beneficial actio...

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Detalles Bibliográficos
Autores principales: Guerra-Menéndez, Lucia, Sádaba, Maria C, Puche, Juan E, Lavandera, Jose L, de Castro, Luis F, de Gortázar, Arancha R, Castilla-Cortázar, Inma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231608/
https://www.ncbi.nlm.nih.gov/pubmed/24161214
http://dx.doi.org/10.1186/1479-5876-11-271

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