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A Translation System Reconstituted with Human Factors Proves That Processing of Encephalomyocarditis Virus Proteins 2A and 2B Occurs in the Elongation Phase of Translation without Eukaryotic Release Factors

The genomic RNA of encephalomyocarditis virus (EMCV) encodes a single polyprotein, and the primary scission of the polyprotein occurs between nonstructural proteins 2A and 2B by an unknown mechanism. To gain insight into the mechanism of 2A-2B processing, we first translated the 2A-2B region in vitr...

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Detalles Bibliográficos
Autores principales:	Machida, Kodai, Mikami, Satoshi, Masutani, Mamiko, Mishima, Kurumi, Kobayashi, Tominari, Imataka, Hiroaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2014
Materias:	Protein Synthesis and Degradation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231674/ https://www.ncbi.nlm.nih.gov/pubmed/25258322 http://dx.doi.org/10.1074/jbc.M114.593343

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