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Explicit DNase sequence bias modeling enables high-resolution transcription factor footprint detection
DNaseI footprinting is an established assay for identifying transcription factor (TF)–DNA interactions with single base pair resolution. High-throughput DNase-seq assays have recently been used to detect in vivo DNase footprints across the genome. Multiple computational approaches have been develope...
Autores principales: | Yardımcı, Galip Gürkan, Frank, Christopher L., Crawford, Gregory E., Ohler, Uwe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231734/ https://www.ncbi.nlm.nih.gov/pubmed/25294828 http://dx.doi.org/10.1093/nar/gku810 |
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