Cargando…
Large-scale mapping of sequence-function relations in small regulatory RNAs reveals plasticity and modularity
Two decades into the genomics era the question of mapping sequence to function has evolved from identifying functional elements to characterizing their quantitative properties including, in particular, their specificity and efficiency. Here, we use a large-scale approach to establish a quantitative...
Autores principales: | Peterman, Neil, Lavi-Itzkovitz, Anat, Levine, Erel |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231740/ https://www.ncbi.nlm.nih.gov/pubmed/25262352 http://dx.doi.org/10.1093/nar/gku863 |
Ejemplares similares
-
Quantitative effect of target translation on small RNA efficacy reveals a novel mode of interaction
por: Lavi-Itzkovitz, Anat, et al.
Publicado: (2014) -
Sort-seq under the hood: implications of design choices on large-scale characterization of sequence-function relations
por: Peterman, Neil, et al.
Publicado: (2016) -
Assessing the gene regulatory properties of Argonaute-bound small RNAs of diverse genomic origin
por: Thomson, Daniel W., et al.
Publicado: (2015) -
Auxiliary tRNAs: large-scale analysis of tRNA genes reveals patterns of tRNA repertoire dynamics
por: Wald, Naama, et al.
Publicado: (2014) -
Identification of regulatory RNAs in Bacillus subtilis
por: Irnov, Irnov, et al.
Publicado: (2010)