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Ribosome-controlled transcription termination is essential for the production of antibiotic microcin C

Microcin C (McC) is a peptide–nucleotide antibiotic produced by Escherichia coli cells harboring a plasmid-borne operon mccABCDE. The heptapeptide MccA is converted into McC by adenylation catalyzed by the MccB enzyme. Since MccA is a substrate for MccB, a mechanism that regulates the MccA/MccB rati...

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Detalles Bibliográficos
Autores principales:	Zukher, Inna, Novikova, Maria, Tikhonov, Anton, Nesterchuk, Mikhail V., Osterman, Ilya A., Djordjevic, Marko, Sergiev, Petr V., Sharma, Cynthia M., Severinov, Konstantin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231749/ https://www.ncbi.nlm.nih.gov/pubmed/25274735 http://dx.doi.org/10.1093/nar/gku880

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