The non-canonical hydroxylase structure of YfcM reveals a metal ion-coordination motif required for EF-P hydroxylation

EF-P is a bacterial tRNA-mimic protein, which accelerates the ribosome-catalyzed polymerization of poly-prolines. In Escherichia coli, EF-P is post-translationally modified on a conserved lysine residue. The post-translational modification is performed in a two-step reaction involving the addition o...

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Detalles Bibliográficos
Autores principales: Kobayashi, Kan, Katz, Assaf, Rajkovic, Andrei, Ishii, Ryohei, Branson, Owen E., Freitas, Michael A., Ishitani, Ryuichiro, Ibba, Michael, Nureki, Osamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231759/
https://www.ncbi.nlm.nih.gov/pubmed/25274739
http://dx.doi.org/10.1093/nar/gku898

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