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A genome-wide function of THSC/TREX-2 at active genes prevents transcription–replication collisions

The THSC/TREX-2 complex of Saccharomyces cerevisiae mediates the anchoring of transcribed genes to the nuclear pore, linking transcription elongation with mRNA export and genome stability, as shown for specific reporters. However, it is still unknown whether the function of TREX-2 is global and the...

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Detalles Bibliográficos
Autores principales:	Santos-Pereira, José M., García-Rubio, María L., González-Aguilera, Cristina, Luna, Rosa, Aguilera, Andrés
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231764/ https://www.ncbi.nlm.nih.gov/pubmed/25294824 http://dx.doi.org/10.1093/nar/gku906

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