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Structural requirement of Ntc77 for spliceosome activation and first catalytic step

The Prp19-associated complex is required for spliceosome activation by stabilizing the binding of U5 and U6 on the spliceosome after the release of U4. The complex comprises at least eight proteins, among which Ntc90 and Ntc77 contain multiple tetratricopeptide repeat (TPR) elements. We have previou...

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Detalles Bibliográficos
Autores principales:	Chen, Hsin-Chou, Chang, Kae-Jiun, Su, Yu-Lun, Huang, Yu-Hsin, Cheng, Soo-Chen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231770/ https://www.ncbi.nlm.nih.gov/pubmed/25294830 http://dx.doi.org/10.1093/nar/gku914

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