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ETS1 is a genome-wide effector of RAS/ERK signaling in epithelial cells

The RAS/ERK pathway is commonly activated in carcinomas and promotes oncogenesis by altering transcriptional programs. However, the array of cis-regulatory elements and trans-acting factors that mediate these transcriptional changes is still unclear. Our genome-wide analysis determined that a sequen...

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Detalles Bibliográficos
Autores principales: Plotnik, Joshua P., Budka, Justin A., Ferris, Mary W., Hollenhorst, Peter C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231772/
https://www.ncbi.nlm.nih.gov/pubmed/25294825
http://dx.doi.org/10.1093/nar/gku929