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ETS1 is a genome-wide effector of RAS/ERK signaling in epithelial cells

The RAS/ERK pathway is commonly activated in carcinomas and promotes oncogenesis by altering transcriptional programs. However, the array of cis-regulatory elements and trans-acting factors that mediate these transcriptional changes is still unclear. Our genome-wide analysis determined that a sequen...

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Detalles Bibliográficos
Autores principales:	Plotnik, Joshua P., Budka, Justin A., Ferris, Mary W., Hollenhorst, Peter C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231772/ https://www.ncbi.nlm.nih.gov/pubmed/25294825 http://dx.doi.org/10.1093/nar/gku929

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