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Quantifying the impact of inter-site heterogeneity on the distribution of ChIP-seq data

Chromatin Immunoprecipitation followed by sequencing (ChIP-seq) is a valuable tool for epigenetic studies. Analysis of the data arising from ChIP-seq experiments often requires implicit or explicit statistical modeling of the read counts. The simple Poisson model is attractive, but does not provide...

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Detalles Bibliográficos
Autores principales: Cairns, Jonathan, Lynch, Andy G., Tavaré, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231950/
https://www.ncbi.nlm.nih.gov/pubmed/25452765
http://dx.doi.org/10.3389/fgene.2014.00399