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Acceleration of periosteal bone formation by human basic fibroblast growth factor containing a collagen-binding domain from Clostridium histolyticum collagenase

Basic fibroblast growth factor 2 (bFGF) is a potent mitogen for mesenchymal cells, and the local application of recombinant bFGF accelerates bone union and defect repair. However, repeated dosing is required for sustained therapeutic effect as the efficacy of bFGF decreases rapidly following its dif...

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Detalles Bibliográficos
Autores principales: Uchida, Kentaro, Matsushita, Osamu, Naruse, Kouji, Mima, Takehiko, Nishi, Nozomu, Hattori, Shunji, Ogura, Takayuki, Inoue, Gen, Tanaka, Keisuke, Takaso, Masashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232007/
https://www.ncbi.nlm.nih.gov/pubmed/23775724
http://dx.doi.org/10.1002/jbm.a.34841