The Janus transcription factor HapX controls fungal adaptation to both iron starvation and iron excess

Balance of physiological levels of iron is essential for every organism. In Aspergillus fumigatus and other fungal pathogens, the transcription factor HapX mediates adaptation to iron limitation and consequently virulence by repressing iron consumption and activating iron uptake. Here, we demonstrat...

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Detalles Bibliográficos
Autores principales: Gsaller, Fabio, Hortschansky, Peter, Beattie, Sarah R, Klammer, Veronika, Tuppatsch, Katja, Lechner, Beatrix E, Rietzschel, Nicole, Werner, Ernst R, Vogan, Aaron A, Chung, Dawoon, Mühlenhoff, Ulrich, Kato, Masashi, Cramer, Robert A, Brakhage, Axel A, Haas, Hubertus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232046/
https://www.ncbi.nlm.nih.gov/pubmed/25092765
http://dx.doi.org/10.15252/embj.201489468

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