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Spinal ephrinB/EphB signalling contributed to remifentanil-induced hyperalgesia via NMDA receptor

BACKGROUND: One of the major unresolved issues in treating pain is the paradoxical hyperalgesia produced by opiates, and accumulating evidence implicate that EphBs receptors and ephrinBs ligands are involved in mediation of spinal nociceptive information and central sensitization, but the manner in...

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Detalles Bibliográficos
Autores principales: Xia, WS, Peng, YN, Tang, LH, Jiang, LS, Yu, LN, Zhou, XL, Zhang, FJ, Yan, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232047/
https://www.ncbi.nlm.nih.gov/pubmed/24737575
http://dx.doi.org/10.1002/j.1532-2149.2014.00478.x