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Boolean Modelling Reveals New Regulatory Connections between Transcription Factors Orchestrating the Development of the Ventral Spinal Cord

We have assembled a network of cell-fate determining transcription factors that play a key role in the specification of the ventral neuronal subtypes of the spinal cord on the basis of published transcriptional interactions. Asynchronous Boolean modelling of the network was used to compare simulatio...

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Detalles Bibliográficos
Autores principales: Lovrics, Anna, Gao, Yu, Juhász, Bianka, Bock, István, Byrne, Helen M., Dinnyés, András, Kovács, Krisztián A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232242/
https://www.ncbi.nlm.nih.gov/pubmed/25398016
http://dx.doi.org/10.1371/journal.pone.0111430