Real-Time Monitoring of New Delhi Metallo-β-Lactamase Activity in Living Bacterial Cells by (1)H NMR Spectroscopy**

Disconnections between in vitro responses and those observed in whole cells confound many attempts to design drugs in areas of serious medical need. A method based on 1D (1)H NMR spectroscopy is reported that affords the ability to monitor the hydrolytic decomposition of the carbapenem antibiotic me...

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Detalles Bibliográficos
Autores principales: Ma, Junhe, McLeod, Sarah, MacCormack, Kathleen, Sriram, Shubha, Gao, Ning, Breeze, Alexander L, Hu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2014
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232273/
https://www.ncbi.nlm.nih.gov/pubmed/24458501
http://dx.doi.org/10.1002/anie.201308636

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