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Construction and Application of a Korean Reference Panel for Imputing Classical Alleles and Amino Acids of Human Leukocyte Antigen Genes

Genetic variations of human leukocyte antigen (HLA) genes within the major histocompatibility complex (MHC) locus are strongly associated with disease susceptibility and prognosis for many diseases, including many autoimmune diseases. In this study, we developed a Korean HLA reference panel for impu...

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Detalles Bibliográficos
Autores principales: Kim, Kwangwoo, Bang, So-Young, Lee, Hye-Soon, Bae, Sang-Cheol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232350/
https://www.ncbi.nlm.nih.gov/pubmed/25398076
http://dx.doi.org/10.1371/journal.pone.0112546