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A systematic review and meta-analysis of 130,000 individuals shows smoking does not modify the association of APOE genotype on risk of coronary heart disease

BACKGROUND: Conflicting evidence exists on whether smoking acts as an effect modifier of the association between APOE genotype and risk of coronary heart disease (CHD). METHODS AND RESULTS: We searched PubMed and EMBASE to June 11, 2013 for published studies reporting APOE genotype, smoking status a...

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Detalles Bibliográficos
Autores principales:	Holmes, Michael V., Frikke-Schmidt, Ruth, Melis, Daniela, Luben, Robert, Asselbergs, Folkert W., Boer, Jolanda M.A., Cooper, Jackie, Palmen, Jutta, Horvat, Pia, Engmann, Jorgen, Li, Ka-Wah, Onland-Moret, N. Charlotte, Hofker, Marten H., Kumari, Meena, Keating, Brendan J., Hubacek, Jaroslav A., Adamkova, Vera, Kubinova, Ruzena, Bobak, Martin, Khaw, Kay-Tee, Nordestgaard, Børge G., Wareham, Nick, Humphries, Steve E., Langenberg, Claudia, Tybjaerg-Hansen, Anne, Talmud, Philippa J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232362/ https://www.ncbi.nlm.nih.gov/pubmed/25173947 http://dx.doi.org/10.1016/j.atherosclerosis.2014.07.038

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