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Zinc-Finger Nuclease Knockout of Dual-Specificity Protein Phosphatase-5 Enhances the Myogenic Response and Autoregulation of Cerebral Blood Flow in FHH.1(BN) Rats

We recently reported that the myogenic responses of the renal afferent arteriole (Af-Art) and middle cerebral artery (MCA) and autoregulation of renal and cerebral blood flow (RBF and CBF) were impaired in Fawn Hooded hypertensive (FHH) rats and were restored in a FHH.1(BN) congenic strain in which...

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Detalles Bibliográficos
Autores principales:	Fan, Fan, Geurts, Aron M., Pabbidi, Mallikarjuna R., Smith, Stanley V., Harder, David R., Jacob, Howard, Roman, Richard J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232417/ https://www.ncbi.nlm.nih.gov/pubmed/25397684 http://dx.doi.org/10.1371/journal.pone.0112878

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