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A New Recombinant BCG Vaccine Induces Specific Th17 and Th1 Effector Cells with Higher Protective Efficacy against Tuberculosis
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (Mtb) that is a major public health problem. The vaccine used for TB prevention is Mycobacterium bovis bacillus Calmette-Guérin (BCG), which provides variable efficacy in protecting against pulmonary TB among adults. Con...
Autores principales: | da Costa, Adeliane Castro, Costa-Júnior, Abadio de Oliveira, de Oliveira, Fábio Muniz, Nogueira, Sarah Veloso, Rosa, Joseane Damaceno, Resende, Danilo Pires, Kipnis, André, Junqueira-Kipnis, Ana Paula |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232451/ https://www.ncbi.nlm.nih.gov/pubmed/25398087 http://dx.doi.org/10.1371/journal.pone.0112848 |
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