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Spatial encoding of cyclic AMP signalling specificity by GPCR endocytosis
G protein-coupled receptors (GPCRs) are well known to signal via cyclic AMP (cAMP) production at the plasma membrane, but it is now clear that various GPCRs also signal after internalization. Apart from its temporal impact through prolonging the cellular response, does the endosome-initiated signal...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232470/ https://www.ncbi.nlm.nih.gov/pubmed/25362359 http://dx.doi.org/10.1038/nchembio.1665 |