Cargando…

Ligand Binding Reveals a Role for Heme in Translationally-Controlled Tumor Protein Dimerization

The translationally-controlled tumor protein (TCTP) is a highly conserved, ubiquitously expressed, abundant protein that is broadly distributed among eukaryotes. Its biological function spans numerous cellular processes ranging from regulation of the cell cycle and microtubule stabilization to cell...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lucas, Andrew T., Fu, Xiangping, Liu, JingJing, Brannon, Mary K., Yang, Jianhua, Capelluto, Daniel G. S., Finkielstein, Carla V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232476/ https://www.ncbi.nlm.nih.gov/pubmed/25396429 http://dx.doi.org/10.1371/journal.pone.0112823

Ejemplares similares

Chronotherapy: Intuitive, Sound, Founded…But Not Broadly Applied
por: Selfridge, Julia M., et al.
Publicado: (2016)

Opening the Debate: How to Fulfill the Need for Physicians’ Training in Circadian-Related Topics in a Full Medical School Curriculum
por: Selfridge, Julia M, et al.
Publicado: (2015)

Membrane targeting of TIRAP is negatively regulated by phosphorylation in its phosphoinositide-binding motif
por: Zhao, Xiaolin, et al.
Publicado: (2017)

Sulfatides Partition Disabled-2 in Response to Platelet Activation
por: Drahos, Karen E., et al.
Publicado: (2009)

The heme-regulated inhibitor kinase requires dimerization for heme-sensing activity
por: Ricketts, M. Daniel, et al.
Publicado: (2022)

Dimerization and Heme Binding Are Conserved in Amphibian and Starfish Homologues of the microRNA Processing Protein DGCR8
por: Senturia, Rachel, et al.
Publicado: (2012)

Ligand binding by the tandem glycine riboswitch depends on aptamer dimerization but not double ligand occupancy
por: Ruff, Karen M., et al.
Publicado: (2014)

Protein Folding Modulates the Swapped Dimerization Mechanism of Methyl-Accepting Chemotaxis Heme Sensors
por: Silva, Marta A., et al.
Publicado: (2012)

Single-molecule photobleaching reveals increased MET receptor dimerization upon ligand binding in intact cells
por: Dietz, Marina S, et al.
Publicado: (2013)

Shapes and Patterns of Heme-Binding Motifs in Mammalian Heme-Binding Proteins
por: Rathod, Dhruv C., et al.
Publicado: (2023)

Heme orientation modulates histidine dissociation and ligand binding kinetics in the hexacoordinated human neuroglobin
por: Bocahut, Anthony, et al.
Publicado: (2012)

Correction: Protein Folding Modulates the Swapped Dimerization Mechanism of Methyl-Accepting Chemotaxis Heme Sensors
por: Silva, Marta A., et al.
Publicado: (2013)

Structural, in silico, and functional analysis of a Disabled-2-derived peptide for recognition of sulfatides
por: Song, Wei, et al.
Publicado: (2020)

Dimerized Translationally Controlled Tumor Protein-Binding Peptide Ameliorates Atopic Dermatitis in NC/Nga Mice
por: Jin, Xing-Hai, et al.
Publicado: (2017)

The circadian factor Period 2 modulates p53 stability and transcriptional activity in unstressed cells
por: Gotoh, Tetsuya, et al.
Publicado: (2014)

Activation of signaling receptors: do ligands bind to receptor monomer, dimer, or both?
por: Pang, Xiaodong, et al.
Publicado: (2013)

Molecular mechanisms of human IRE1 activation through dimerization and ligand binding
por: Joshi, Amar, et al.
Publicado: (2015)

A general model for predicting the binding affinity of reversibly and irreversibly dimerized ligands
por: Foreman, Kenneth W.
Publicado: (2017)

The effect of dimerization and ligand binding on the dynamics of Kaposi's sarcoma‐associated herpesvirus protease
por: Bern, David, et al.
Publicado: (2022)

The repertoire of protein-sulfatide interactions reveal distinct modes of sulfatide recognition
por: Capelluto, Daniel G. S
Publicado: (2022)

TLR4 Signaling by Heme and the Role of Heme-Binding Blood Proteins
por: Janciauskiene, Sabina, et al.
Publicado: (2020)

Analysis of Fluctuation in the Heme-Binding Pocket and Heme Distortion in Hemoglobin and Myoglobin
por: Kondo, Hiroko X., et al.
Publicado: (2022)

Phafins Are More Than Phosphoinositide-Binding Proteins
por: Tang, Tuoxian, et al.
Publicado: (2023)

ErbB1 dimerization is promoted by domain co-confinement and stabilized by ligand-binding
por: Low-Nam, Shalini T., et al.
Publicado: (2011)

Allosteric activation of preformed EGF receptor dimers by a single ligand binding event
por: Purba, Endang R., et al.
Publicado: (2022)

A Structural Comparison of SARS-CoV-2 Main Protease and Animal Coronaviral Main Protease Reveals Species-Specific Ligand Binding and Dimerization Mechanism
por: Ho, Chien-Yi, et al.
Publicado: (2022)

The surface protein Shr of Streptococcus pyogenes binds heme and transfers it to the streptococcal heme-binding protein Shp
por: Zhu, Hui, et al.
Publicado: (2008)

HemeBIND: a novel method for heme binding residue prediction by combining structural and sequence information
por: Liu, Rong, et al.
Publicado: (2011)

Comprehensive Fe–Ligand Vibration Identification in {FeNO}(6) Hemes
por: Li, Jianfeng, et al.
Publicado: (2014)

Modulation of ligand–heme reactivity by binding pocket residues demonstrated in cytochrome c' over the femtosecond–second temporal range
por: Russell, Henry J., et al.
Publicado: (2013)

Characterization of the Heme Pocket Structure and Ligand Binding Kinetics of Non-symbiotic Hemoglobins from the Model Legume Lotus japonicus
por: Calvo-Begueria, Laura, et al.
Publicado: (2017)

New TSPO Crystal Structures of Mutant and Heme-Bound Forms with Altered Flexibility, Ligand Binding, and Porphyrin Degradation Activity
por: Liu, Jian, et al.
Publicado: (2023)

Dimerization of Translationally Controlled Tumor Protein Is Essential For Its Cytokine-Like Activity
por: Kim, Miyoung, et al.
Publicado: (2009)

Allergic Inflammation Caused by Dimerized Translationally Controlled Tumor Protein is Attenuated by Cardamonin
por: Pyun, Haejun, et al.
Publicado: (2021)

Impact of Glucocorticoid Receptor Density on Ligand-Independent Dimerization, Cooperative Ligand-Binding and Basal Priming of Transactivation: A Cell Culture Model
por: Robertson, Steven, et al.
Publicado: (2013)

β-Lactoglobulin's Conformational Requirements for Ligand Binding at the Calyx and the Dimer Interphase: a Flexible Docking Study
por: Domínguez-Ramírez, Lenin, et al.
Publicado: (2013)

Assessing G4-Binding Ligands In Vitro and in Cellulo Using Dimeric Carbocyanine Dye Displacement Assay
por: Desai, Nakshi, et al.
Publicado: (2021)

Heme activation by DNA: isoguanine pentaplexes, but not quadruplexes, bind heme and enhance its oxidative activity
por: Shumayrikh, Nisreen, et al.
Publicado: (2015)

Binding asymmetry and conformational studies of the AtGSDA dimer
por: Jia, Qian, et al.
Publicado: (2023)

The Crystal Structure of the Orphan Nuclear Receptor NR2E3/PNR Ligand Binding Domain Reveals a Dimeric Auto-Repressed Conformation
por: Tan, M. H. Eileen, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_hnjk42osut0vkpkdnclce70tcu