Whole Blood Transcriptional Profiling Reveals Deregulation of Oxidative and Antioxidative Defence Genes in Myelofibrosis and Related Neoplasms. Potential Implications of Downregulation of Nrf2 for Genomic Instability and Disease Progression

The Philadelphia-negative chronic myeloproliferative neoplasms - essential thrombocythemia (ET), polycythemia vera (PV), and myelofibrosis (MF) (MPNs) - have recently been shown to be associated with chronic inflammation, oxidative stress and accumulation of reactive oxygen species (ROS). Using whol...

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Detalles Bibliográficos
Autores principales: Hasselbalch, Hans Carl, Thomassen, Mads, Hasselbalch Riley, Caroline, Kjær, Lasse, Stauffer Larsen, Thomas, Jensen, Morten K., Bjerrum, Ole Weis, Kruse, Torben A., Skov, Vibe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232509/
https://www.ncbi.nlm.nih.gov/pubmed/25397683
http://dx.doi.org/10.1371/journal.pone.0112786

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232509/
https://www.ncbi.nlm.nih.gov/pubmed/25397683
http://dx.doi.org/10.1371/journal.pone.0112786

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