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The Supraspliceosome — A Multi-Task Machine for Regulated Pre-mRNA Processing in the Cell Nucleus

Pre-mRNA splicing of Pol II transcripts is executed in the mammalian cell nucleus within a huge (21 MDa) and highly dynamic RNP machine — the supraspliceosome. It is composed of four splicing active native spliceosomes, each resembling an in vitro assembled spliceosome, which are connected by the pr...

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Detalles Bibliográficos
Autores principales:	Shefer, Kinneret, Sperling, Joseph, Sperling, Ruth
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Research Network of Computational and Structural Biotechnology 2014
Materias:	Mini Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232567/ https://www.ncbi.nlm.nih.gov/pubmed/25408845 http://dx.doi.org/10.1016/j.csbj.2014.09.008

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