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The E3 ubiquitin ligase RNF121 is a positive regulator of NF-κB activation
BACKGROUND: The nuclear factor κB (NF-κB) family members regulate several biological processes as cell proliferation and differentiation, inflammation, immunity and tumor progression. Ubiquitination plays a key role in NF-κB activation and the ubiquitylated transmitters of the NF-κB signaling cascad...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232610/ https://www.ncbi.nlm.nih.gov/pubmed/25388546 http://dx.doi.org/10.1186/s12964-014-0072-8 |