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SIRT1 activator (SRT1720) improves the follicle reserve and prolongs the ovarian lifespan of diet-induced obesity in female mice via activating SIRT1 and suppressing mTOR signaling

BACKGROUND: The prevalence of obesity is increasing worldwide and significantly affects fertility and reproduction in both men and women. Our recent study has shown that excess body fat accelerates ovarian follicle development and follicle loss in rats. The aim of the present study is to explore the...

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Detalles Bibliográficos
Autores principales:	Zhou, Xiao-Ling, Xu, Jin-Jie, Ni, Yan-Hong, Chen, Xiao-Chun, Zhang, Hong-Xia, Zhang, Xing-Mei, Liu, Wei-Juan, Luo, Li-Li, Fu, Yu-Cai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232623/ https://www.ncbi.nlm.nih.gov/pubmed/25330910 http://dx.doi.org/10.1186/s13048-014-0097-z

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