Cargando…
Benchmarking mutation effect prediction algorithms using functionally validated cancer-related missense mutations
BACKGROUND: Massively parallel sequencing studies have led to the identification of a large number of mutations present in a minority of cancers of a given site. Hence, methods to identify the likely pathogenic mutations that are worth exploring experimentally and clinically are required. We sought...
| Autores principales: | , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232638/ https://www.ncbi.nlm.nih.gov/pubmed/25348012 http://dx.doi.org/10.1186/s13059-014-0484-1 |