A mutation in Ampd2 is associated with nephrotic syndrome and hypercholesterolemia in mice

BACKGROUND: Previously, we identified three loci affecting HDL-cholesterol levels in a screen for ENU-induced mutations in mice and discovered two mutated genes. We sought to identify the third mutated gene and further characterize the mouse phenotype. METHODS: We engaged, DNA sequencing, gene expre...

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Detalles Bibliográficos
Autores principales: Helmering, Joan, Juan, Todd, Li, Chi Ming, Chhoa, Mark, Baron, Will, Gyuris, Tibor, Richards, William G, Turk, James R, Lawrence, Jeff, Cosgrove, Patrick A, Busby, Jim, Kim, Ki Won, Kaufman, Stephen A, Cummings, Connie, Carlson, George, Véniant, Murielle M, Lloyd, David J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232700/
https://www.ncbi.nlm.nih.gov/pubmed/25361754
http://dx.doi.org/10.1186/1476-511X-13-167

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