Cargando…
Nucleotide synthesis is regulated by cytoophidium formation during neurodevelopment and adaptive metabolism
The essential metabolic enzyme CTP synthase (CTPsyn) can be compartmentalised to form an evolutionarily-conserved intracellular structure termed the cytoophidium. Recently, it has been demonstrated that the enzymatic activity of CTPsyn is attenuated by incorporation into cytoophidia in bacteria and...
Autores principales: | Aughey, Gabriel N., Grice, Stuart J., Shen, Qing-Ji, Xu, Yichi, Chang, Chia-Chun, Azzam, Ghows, Wang, Pei-Yu, Freeman-Mills, Luke, Pai, Li-Mei, Sung, Li-Ying, Yan, Jun, Liu, Ji-Long |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232762/ https://www.ncbi.nlm.nih.gov/pubmed/25326513 http://dx.doi.org/10.1242/bio.201410165 |
Ejemplares similares
-
Only One Isoform of Drosophila melanogaster CTP Synthase Forms the Cytoophidium
por: Azzam, Ghows, et al.
Publicado: (2013) -
Cytoophidium assembly reflects upregulation of IMPDH activity
por: Chang, Chia-Chun, et al.
Publicado: (2015) -
The TOR pathway modulates cytoophidium formation in Schizosaccharomyces pombe
por: Andreadis, Christos, et al.
Publicado: (2019) -
IMP/GTP balance modulates cytoophidium assembly and IMPDH activity
por: Keppeke, Gerson Dierley, et al.
Publicado: (2018) -
Temperature-sensitive cytoophidium assembly in Schizosaccharomyces pombe
por: Zhang, Jing, et al.
Publicado: (2019)