In vitro co-culture systems for studying molecular basis of cellular interaction between Aire-expressing medullary thymic epithelial cells and fresh thymocytes

We previously established three mouse cell lines (Aire(+)TEC1, Aire(+)TEC2 and Aire(+)DC) from the medullary thymic epithelial cells (mTECs) and dendritic cells (mDCs). These cells constitutively expressed “autoimmune regulator (Aire) gene” and they exhibited various features of self antigen-present...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Yoshitaka, Kudoh, Jun, Yoshida, Tetsuhiko, Shimizu, Nobuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232765/
https://www.ncbi.nlm.nih.gov/pubmed/25326516
http://dx.doi.org/10.1242/bio.201410173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232765/
https://www.ncbi.nlm.nih.gov/pubmed/25326516
http://dx.doi.org/10.1242/bio.201410173

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