Preparation of Pluronic/Bile salt/Phospholipid Mixed Micelles as Drug Solubility Enhancer and Study the Effect of the PPO Block Size on the Solubility of Pyrene

Pluronic/bile salt/phospholipid mixed micelles (Pluronic/BS/PS-MM) drug carrier system for solubilization hydrophobic drugs was developed. A typical hydrophobic compound, pyrene, was selected as a representative hydrophobic compound to model the hydrophobic drugs. Five Pluronics, F68, F88, F98, F108...

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Detalles Bibliográficos
Autores principales: Wang, Li, Peng, Min, Zhu, Yuan, Tong, Shan-shan, Cao, Xia, Xu, Xi-ming, Yu, Jiang-nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2014
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Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232780/
https://www.ncbi.nlm.nih.gov/pubmed/25587303

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