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Thiopurine withdrawal during sustained clinical remission in inflammatory bowel disease: relapse and recapture rates, with predictive factors in 237 patients
BACKGROUND: Thiopurines (azathioprine and mercaptopurine) remain integral to most medical strategies for maintaining remission in Crohn's disease (CD) and ulcerative colitis (UC). Indefinite use of these drugs is tempered by long-term risks. While clinical relapse is noted frequently following...
Autores principales: | Kennedy, N A, Kalla, R, Warner, B, Gambles, C J, Musy, R, Reynolds, S, Dattani, R, Nayee, H, Felwick, R, Harris, R, Marriott, S, Senanayake, S M, Lamb, C A, Al-Hilou, H, Gaya, D R, Irving, P M, Mansfield, J, Parkes, M, Ahmad, T, Cummings, J R F, Arnott, I D, Satsangi, J, Lobo, A J, Smith, M, Lindsay, J O, Lees, C W |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232866/ https://www.ncbi.nlm.nih.gov/pubmed/25284134 http://dx.doi.org/10.1111/apt.12980 |
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