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Exon resequencing of H3K9 methyltransferase complex genes, EHMT1, EHTM2 and WIZ, in Japanese autism subjects
BACKGROUND: Histone H3 methylation at lysine 9 (H3K9) is a conserved epigenetic signal, mediating heterochromatin formation by trimethylation, and transcriptional silencing by dimethylation. Defective GLP (Ehmt1) and G9a (Ehmt2) histone lysine methyltransferases, involved in mono and dimethylation o...
Autores principales: | Balan, Shabeesh, Iwayama, Yoshimi, Maekawa, Motoko, Toyota, Tomoko, Ohnishi, Tetsuo, Toyoshima, Manabu, Shimamoto, Chie, Esaki, Kayoko, Yamada, Kazuo, Iwata, Yasuhide, Suzuki, Katsuaki, Ide, Masayuki, Ota, Motonori, Fukuchi, Satoshi, Tsujii, Masatsugu, Mori, Norio, Shinkai, Yoichi, Yoshikawa, Takeo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233047/ https://www.ncbi.nlm.nih.gov/pubmed/25400900 http://dx.doi.org/10.1186/2040-2392-5-49 |
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