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SOX4 inhibits GBM cell growth and induces G0/G1 cell cycle arrest through Akt-p53 axis
BACKGROUND: SOX4 is a transcription factor required for tissue development and differentiation in vertebrates. Overexpression of SOX4 has been reported in many cancers including glioblastoma multiforme (GBM), however, the underlying mechanism of actions has not been studied. In this study, we invest...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233052/ https://www.ncbi.nlm.nih.gov/pubmed/25366337 http://dx.doi.org/10.1186/s12883-014-0207-y |