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SOX4 inhibits GBM cell growth and induces G0/G1 cell cycle arrest through Akt-p53 axis

BACKGROUND: SOX4 is a transcription factor required for tissue development and differentiation in vertebrates. Overexpression of SOX4 has been reported in many cancers including glioblastoma multiforme (GBM), however, the underlying mechanism of actions has not been studied. In this study, we invest...

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Detalles Bibliográficos
Autores principales:	Zhang, Jing, Jiang, Huawei, Shao, Jiaofang, Mao, Ruifang, Liu, Jie, Ma, Yingying, Fang, Xuefeng, Zhao, Na, Zheng, Shu, Lin, Biaoyang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233052/ https://www.ncbi.nlm.nih.gov/pubmed/25366337 http://dx.doi.org/10.1186/s12883-014-0207-y

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