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Malignant melanoma of the penis and urethra: one case report

We present a case of a patient with malignant melanoma of the glans penis and urethra, which was found in a 53-year-old man with nonhealing ulcerative penile lesion and bilateral, clinically palpable inguinal lymphadenopathies at diagnosis. A diagnostic biopsy showed the characteristics of a melanom...

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Autores principales: Li, Yunxiang, Yuan, Haichao, Wang, Anguo, Zhang, Zongping, Wu, Ji, Wei, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233061/
https://www.ncbi.nlm.nih.gov/pubmed/25385349
http://dx.doi.org/10.1186/1477-7819-12-340
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author Li, Yunxiang
Yuan, Haichao
Wang, Anguo
Zhang, Zongping
Wu, Ji
Wei, Qiang
author_facet Li, Yunxiang
Yuan, Haichao
Wang, Anguo
Zhang, Zongping
Wu, Ji
Wei, Qiang
author_sort Li, Yunxiang
collection PubMed
description We present a case of a patient with malignant melanoma of the glans penis and urethra, which was found in a 53-year-old man with nonhealing ulcerative penile lesion and bilateral, clinically palpable inguinal lymphadenopathies at diagnosis. A diagnostic biopsy showed the characteristics of a melanoma. We treated the patient with total penectomy and bilateral inguinal lymph node dissection. After surgery, chemotherapy with bleomycin, vincristine and cisplatin and immunotherapy with thymosin injection were started. No recurrence or metastasis occurred during the 3 years after the operation. Melanoma of the penis is very rare, and early diagnosis is important because the patient prognosis is very poor.
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spelling pubmed-42330612014-11-17 Malignant melanoma of the penis and urethra: one case report Li, Yunxiang Yuan, Haichao Wang, Anguo Zhang, Zongping Wu, Ji Wei, Qiang World J Surg Oncol Case Report We present a case of a patient with malignant melanoma of the glans penis and urethra, which was found in a 53-year-old man with nonhealing ulcerative penile lesion and bilateral, clinically palpable inguinal lymphadenopathies at diagnosis. A diagnostic biopsy showed the characteristics of a melanoma. We treated the patient with total penectomy and bilateral inguinal lymph node dissection. After surgery, chemotherapy with bleomycin, vincristine and cisplatin and immunotherapy with thymosin injection were started. No recurrence or metastasis occurred during the 3 years after the operation. Melanoma of the penis is very rare, and early diagnosis is important because the patient prognosis is very poor. BioMed Central 2014-11-11 /pmc/articles/PMC4233061/ /pubmed/25385349 http://dx.doi.org/10.1186/1477-7819-12-340 Text en © Li et al.; licensee BioMed Central Ltd. 2014 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Li, Yunxiang
Yuan, Haichao
Wang, Anguo
Zhang, Zongping
Wu, Ji
Wei, Qiang
Malignant melanoma of the penis and urethra: one case report
title Malignant melanoma of the penis and urethra: one case report
title_full Malignant melanoma of the penis and urethra: one case report
title_fullStr Malignant melanoma of the penis and urethra: one case report
title_full_unstemmed Malignant melanoma of the penis and urethra: one case report
title_short Malignant melanoma of the penis and urethra: one case report
title_sort malignant melanoma of the penis and urethra: one case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233061/
https://www.ncbi.nlm.nih.gov/pubmed/25385349
http://dx.doi.org/10.1186/1477-7819-12-340
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