Cargando…

MCRS1 overexpression, which is specifically inhibited by miR-129*, promotes the epithelial-mesenchymal transition and metastasis in non-small cell lung cancer

BACKGROUND: Although tumor invasion and metastasis are both classical hallmarks of cancer malignancy and the major causes of poor clinical outcomes among cancer patients, the underlying master regulators of invasion and metastasis remain largely unknown. In this study, we observed that an overexpres...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Min-Xia, Zhou, Ke-Cheng, Cao, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233086/ https://www.ncbi.nlm.nih.gov/pubmed/25373388 http://dx.doi.org/10.1186/1476-4598-13-245

Ejemplares similares

Nuclear paraspeckle assembly transcript 1 promotes the metastasis and epithelial-mesenchymal transition of hepatoblastoma cells by inhibiting miR-129-5p
por: Fu, Ming-Cui, et al.
Publicado: (2017)

Expression of MCRS1 and MCRS2 and their correlation with serum carcinoembryonic antigen in colorectal cancer
por: Li, Chenguang, et al.
Publicado: (2016)

MiR-124 targets Slug to regulate epithelial–mesenchymal transition and metastasis of breast cancer
por: Liang, Yong-Jun, et al.
Publicado: (2013)

MiR-195 suppresses the metastasis and epithelial–mesenchymal transition of hepatocellular carcinoma by inhibiting YAP
por: Yu, Shuo, et al.
Publicado: (2017)

miR-122 inhibits metastasis and epithelial–mesenchymal transition of non-small-cell lung cancer cells
por: Qin, Haifeng, et al.
Publicado: (2015)

The candidate oncogene (MCRS1) promotes the growth of human lung cancer cells via the miR–155–Rb1 pathway
por: Liu, Minxia, et al.
Publicado: (2015)

miR-573 inhibits prostate cancer metastasis by regulating epithelial-mesenchymal transition
por: Wang, Lin, et al.
Publicado: (2015)

miR-300 inhibits epithelial to mesenchymal transition and metastasis by targeting Twist in human epithelial cancer
por: Yu, Jingshuang, et al.
Publicado: (2014)

MCRS2 represses the transactivation activities of Nrf1
por: Wu, Jia-Long, et al.
Publicado: (2009)

miR-190 suppresses breast cancer metastasis by regulation of TGF-β-induced epithelial–mesenchymal transition
por: Yu, Yue, et al.
Publicado: (2018)

Down-regulation of miR-129-5p via the Twist1-Snail feedback loop stimulates the epithelial-mesenchymal transition and is associated with poor prognosis in breast cancer
por: Yu, Yue, et al.
Publicado: (2015)

Aurora-A regulates MCRS1 function during mitosis
por: Meunier, Sylvain, et al.
Publicado: (2016)

Recent advances in the chemistry of imine-based multicomponent reactions (MCRs)
por: Choudhury, Lokman H., et al.
Publicado: (2011)

MiR-449a suppresses the epithelial-mesenchymal transition and metastasis of hepatocellular carcinoma by multiple targets
por: Chen, Shu-peng, et al.
Publicado: (2015)

MiR‐577 suppresses epithelial‐mesenchymal transition and metastasis of breast cancer by targeting Rab25
por: Yin, Chonggao, et al.
Publicado: (2018)

miR-338-3p inhibits epithelial-mesenchymal transition and metastasis in hepatocellular carcinoma cells
por: Chen, Jing-Song, et al.
Publicado: (2016)

miR-10a suppresses colorectal cancer metastasis by modulating the epithelial-to-mesenchymal transition and anoikis
por: Liu, Yankun, et al.
Publicado: (2017)

Overexpression of SIRT1 promotes metastasis through epithelial-mesenchymal transition in hepatocellular carcinoma
por: Hao, Chong, et al.
Publicado: (2014)

Overexpression of brachyury contributes to tumor metastasis by inducing epithelial-mesenchymal transition in hepatocellular carcinoma
por: Du, Rui, et al.
Publicado: (2014)

The Expression Levels of Circulating miR-129 and miR-203a in Association with Breast Cancer and Related Metastasis
por: Ghalkhani, Esmat, et al.
Publicado: (2022)

Hyperglycemia induces miR-26-5p down-regulation to overexpress PFKFB3 and accelerate epithelial–mesenchymal transition in gastric cancer
por: He, Xiaobo, et al.
Publicado: (2022)

miR-136 targets MIEN1 and involves the metastasis of colon cancer by suppressing epithelial-to-mesenchymal transition
por: Ren, Haipeng, et al.
Publicado: (2017)

miR-296 inhibits the metastasis and epithelial-mesenchymal transition of colorectal cancer by targeting S100A4
por: He, Zheng, et al.
Publicado: (2017)

The SNAIL/miR-128 axis regulated growth, invasion, metastasis, and epithelial-to-mesenchymal transition of gastric cancer
por: Yu, Wei-Wei, et al.
Publicado: (2017)

MicroRNA miR-509-3p inhibit metastasis and epithelial-mesenchymal transition in hepatocellular carcinoma
por: Zhang, Huiming, et al.
Publicado: (2021)

MCRS1 associates with cytoplasmic dynein and mediates pericentrosomal material recruitment
por: Lee, Si-Hyung, et al.
Publicado: (2016)

miR-32 inhibits proliferation, epithelial–mesenchymal transition, and metastasis by targeting TWIST1 in non-small-cell lung cancer cells
por: Li, Lei, et al.
Publicado: (2016)

MiR-182-5p promotes the Metastasis and Epithelial-mesenchymal Transition in Non-small Cell Lung Cancer by Targeting EPAS1
por: Yang, Wenxiao, et al.
Publicado: (2021)

miR-31 Functions as an Oncomir Which Promotes Epithelial-Mesenchymal Transition via Regulating BAP1 in Cervical Cancer
por: Wang, Nan, et al.
Publicado: (2017)

Mechanism of epithelial-mesenchymal transition inhibited by miR-203 in non-small cell lung cancer
por: Huang, Weicong, et al.
Publicado: (2020)

Overexpression of lncRNA HOXA11-AS promotes cell epithelial–mesenchymal transition by repressing miR-200b in non-small cell lung cancer
por: Chen, Jian-Hui, et al.
Publicado: (2017)

Overexpression of the VRK1 kinase, which is associated with breast cancer, induces a mesenchymal to epithelial transition in mammary epithelial cells
por: Mon, Aye M., et al.
Publicado: (2018)

Mesenchymal stromal cells facilitate resolution of pulmonary fibrosis by miR-29c and miR-129 intercellular transfer
por: Nataliya, Basalova, et al.
Publicado: (2023)

Overexpression of Cathepsin Z Contributes to Tumor Metastasis by Inducing Epithelial-Mesenchymal Transition in Hepatocellular Carcinoma
por: Wang, Jian, et al.
Publicado: (2011)

Epithelial–mesenchymal transition in tumor metastasis
por: Yeung, Kay T., et al.
Publicado: (2016)

EGF-Mediated Overexpression of Myc Attenuates miR-26b by Recruiting HDAC3 to Induce Epithelial-Mesenchymal Transition of Lens Epithelial Cells
por: Dong, Ning, et al.
Publicado: (2018)

miR-486-5p suppresses prostate cancer metastasis by targeting Snail and regulating epithelial–mesenchymal transition
por: Zhang, Xiaoguang, et al.
Publicado: (2016)

The Kindlin-2 regulation of epithelial-to-mesenchymal transition in breast cancer metastasis is mediated through miR-200b
por: Sossey-Alaoui, Khalid, et al.
Publicado: (2018)

hsa-miR-24 suppresses metastasis in nasopharyngeal carcinoma by regulating the c-Myc/epithelial-mesenchymal transition axis
por: Su, Bojin, et al.
Publicado: (2018)

miR-551b regulates epithelial-mesenchymal transition and metastasis of gastric cancer by inhibiting ERBB4 expression
por: Song, Guangyuan, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_2unr1fj7hnqkrlk2872j929o8a