The long reach of telomeres

The primary purpose of telomeres is to protect chromosome ends from erosion during cell division cycles. New observations suggest an additional function for telomeres, namely in gene silencing via formation of long-range chromatin interactions.

Detalles Bibliográficos
Autor principal: Misteli, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233237/
https://www.ncbi.nlm.nih.gov/pubmed/25403176
http://dx.doi.org/10.1101/gad.254573.114
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author Misteli, Tom
author_facet Misteli, Tom
author_sort Misteli, Tom
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description The primary purpose of telomeres is to protect chromosome ends from erosion during cell division cycles. New observations suggest an additional function for telomeres, namely in gene silencing via formation of long-range chromatin interactions.
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spelling pubmed-42332372015-05-15 The long reach of telomeres Misteli, Tom Genes Dev Perspective The primary purpose of telomeres is to protect chromosome ends from erosion during cell division cycles. New observations suggest an additional function for telomeres, namely in gene silencing via formation of long-range chromatin interactions. Cold Spring Harbor Laboratory Press 2014-11-15 /pmc/articles/PMC4233237/ /pubmed/25403176 http://dx.doi.org/10.1101/gad.254573.114 Text en Published by Cold Spring Harbor Laboratory Press http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first six months after the full-issue publication date (see http://genesdev.cshlp.org/site/misc/terms.xhtml). After six months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Perspective
Misteli, Tom
The long reach of telomeres
title The long reach of telomeres
title_full The long reach of telomeres
title_fullStr The long reach of telomeres
title_full_unstemmed The long reach of telomeres
title_short The long reach of telomeres
title_sort long reach of telomeres
topic Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233237/
https://www.ncbi.nlm.nih.gov/pubmed/25403176
http://dx.doi.org/10.1101/gad.254573.114
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