Immunohistochemistry with the anti-BRAF V600E (VE1) antibody: impact of pre-analytical conditions and concordance with DNA sequencing in colorectal and papillary thyroid carcinoma

SUMMARY: The most common of all activating BRAF mutations (T1799A) leads to a substitution of valine (V) to glutamic acid (E) at the position 600 of the amino acid sequence. The major goal of this study was to compare detection of the BRAF V600E mutation by DNA sequencing with immunohistochemistry (...

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Detalles Bibliográficos
Autores principales: Dvorak, Katerina, Aggeler, Birte, Palting, John, McKelvie, Penny, Ruszkiewicz, Andrew, Waring, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2014
Materias:
Anatomical Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233678/
https://www.ncbi.nlm.nih.gov/pubmed/25014730
http://dx.doi.org/10.1097/PAT.0000000000000119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233678/
https://www.ncbi.nlm.nih.gov/pubmed/25014730
http://dx.doi.org/10.1097/PAT.0000000000000119

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