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Quantifying the correlation between spatially defined oxygen gradients and cell fate in an engineered three-dimensional culture model
A challenge in three-dimensional tissue culture remains the lack of quantitative information linking nutrient delivery and cellular distribution. Both in vivo and in vitro, oxygen is delivered by diffusion from its source (blood vessel or the construct margins). The oxygen level at a defined distanc...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233699/ https://www.ncbi.nlm.nih.gov/pubmed/24966240 http://dx.doi.org/10.1098/rsif.2014.0501 |